Overview

Sinclair Research offers specialty biomedical research services in a large range of species encompassing most categories of applied human and veterinary medicine. Preclinical research services and preclinical studies compose a significant portion of our repertoire. Our uniqueness includes our broad experience, the availability of multiple animal models, and the largest herds of miniature swine in the United States. We remain flexible and can tailor our efforts to almost any special procedure that is requested or designed. We strive to retain our customers through competitive cost, strong communication, timeliness, and responsive programs.

History

Sinclair Research Center is a privately owned biomedical research facility located in Central Missouri. Sinclair was formed in 1964 by the University of Missouri and originally named the Sinclair Comparative Medical Research Farm (SCMRF). Its primary function was to provide laboratory animal research support for the University’s Environmental Health Surveillance Center (EHSC) and the Environmental Trace Substance Research Center (ETSRC). These three entities collaborated to monitor for epidemiological evidences of environmental related illnesses (EHSC), analyzing samples to detect trace amounts of substances that could be related to illnesses (ETSRC), and the use of laboratory animal models to test the hypotheses (SCMRF). This environmental toxicology services concept was remarkably farsighted and it remains valid today. 

Through the years, Sinclair’s role expanded and became a resource for a wide variety of human and animal health related research and became deeply involved in the development and use of animal models. The private sector quickly realized the unique resource of Sinclair and dedicated professionals privatized Sinclair Research Center on March 1st 1994 as a successful contract research organization (CRO) and animal production facility.

Sinclair is committed to efficiency, confidentiality, and rapid, accurate service. Our desire is to work closely with our clients to achieve long-term mutually beneficial relationships.

Regulatory Compliance & Quality Assurance

Sinclair is fully GLP-compliant and our personnel have many years of GLP experience. Sinclair has an independent Quality Assurance Unit that audits the facility, protocols, in-life critical phases, raw data, and reports for GLP studies. Sinclair is inspected by the FDA on a regular basis.

Sinclair utilizes the following data capture and SEND dataset creation systems:

• Pristima® Version 7.1 or newer
• SEND Savante ™ 7.4.0 BUILD 16

Sinclair Research Center is proud to offer GLP data sets in SEND (Standard for Exchange of Nonclinical Data) format for submission to the FDA, which supports faster and better quality regulatory review. We use Xybion’s suite of programs, notably Pristima® and SEND Savante™ for quality data acquisition, reporting and dataset creation. Our dedicated study data team works in-house to ensure your data, from collection to submission, is accurately converted to SEND format. Systems are validated and have been assessed for 21 CFR Part 11 compliance. Data capture using the Xybion suite of programs allows Sinclair to provide cost effective and compliant management and oversight of studies.

Sinclair has a Strong Commitment to Animal Welfare

At Sinclair we are all strongly committed to animal welfare and we have a documented quality animal care program that includes a ‘Code of Respect’ for all our animals. Our commitment to adhere to and exceed the highest ethical and scientific standards is demonstrated by our outstanding veterinary care program, our full compliance with the Animal Welfare Act, and our accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International).